Hindquarters Vasoconstriction Through Central GABAB Receptors in Conscious Rats
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چکیده
منابع مشابه
Mesenteric vasoconstriction and hindquarters vasodilatation accompany the pressor actions of exendin-4 in conscious rats.
The hemodynamic effects of the glucagon-like peptide-1 (GLP-1) receptor agonist, exendin-4, and putative underlying mechanisms were assessed in conscious male Sprague-Dawley rats. At a dose of 25 ng kg(-1) i.v., exendin-4 had little effect, but doses of 250 and 2500 ng kg(-1) had significant tachycardic effects (+66 +/- 9 and +95 +/- 16 beats min(-1) at 5 min, respectively) and pressor actions ...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2003
ISSN: 0958-0670
DOI: 10.1113/eph8802574